Targeted gadolinium-loaded dendrimer nanoparticles for tumor-specific magnetic resonance contrast enhancement

A target-specific MRI contrast agent for tumor cells expressing high affinity folate receptor was synthesized using generation five (G5) of polyamidoamine (PAMAM) dendrimer. Surface modified dendrimer was functionalized for targeting with folic acid (FA) and the remaining terminal primary amines of...

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Detalles Bibliográficos
Autores principales: Swanson, Scott D, Kukowska-Latallo, Jolanta F, Patri, Anil K, Chen, Chunyan, Ge, Song, Cao, Zhengyi, Kotlyar, Alina, East, Andrea T, Baker, James R
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527674/
https://www.ncbi.nlm.nih.gov/pubmed/18686779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527674/
https://www.ncbi.nlm.nih.gov/pubmed/18686779

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