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The transforming mutation E17K/AKT1 is not a major event in B-cell-derived lymphoid leukaemias
Despite the major role of the AKT/PKB family of proteins in the regulation of many growth and survival mechanisms in the cell, and the increasing evidence suggesting that AKT disruption could play a key role in many human malignancies, no major mutations of AKT genes had been reported, until very re...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527790/ https://www.ncbi.nlm.nih.gov/pubmed/18665177 http://dx.doi.org/10.1038/sj.bjc.6604512 |