The transforming mutation E17K/AKT1 is not a major event in B-cell-derived lymphoid leukaemias

Despite the major role of the AKT/PKB family of proteins in the regulation of many growth and survival mechanisms in the cell, and the increasing evidence suggesting that AKT disruption could play a key role in many human malignancies, no major mutations of AKT genes had been reported, until very re...

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Detalles Bibliográficos
Autores principales: Mahmoud, I S, Sughayer, M A, Mohammad, H A, Eshtayeh, A A, Awidi, A S, EL-Khateeb, M S, Ismail, S I
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527790/
https://www.ncbi.nlm.nih.gov/pubmed/18665177
http://dx.doi.org/10.1038/sj.bjc.6604512

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