Tumour-targeted nanomedicines: principles and practice

Drug targeting systems are nanometre-sized carrier materials designed for improving the biodistribution of systemically applied (chemo)therapeutics. Various different tumour-targeted nanomedicines have been evaluated over the years, and clear evidence is currently available for substantial improveme...

Descripción completa

Detalles Bibliográficos
Autores principales: Lammers, T, Hennink, W E, Storm, G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527811/
https://www.ncbi.nlm.nih.gov/pubmed/18648371
http://dx.doi.org/10.1038/sj.bjc.6604483
_version_ 1782158842140819456
author Lammers, T
Hennink, W E
Storm, G
author_facet Lammers, T
Hennink, W E
Storm, G
author_sort Lammers, T
collection PubMed
description Drug targeting systems are nanometre-sized carrier materials designed for improving the biodistribution of systemically applied (chemo)therapeutics. Various different tumour-targeted nanomedicines have been evaluated over the years, and clear evidence is currently available for substantial improvement of the therapeutic index of anticancer agents. Here, we briefly summarise the most important targeting systems and strategies, and discuss recent advances and future directions in the development of tumour-targeted nanomedicines.
format Text
id pubmed-2527811
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-25278112009-09-11 Tumour-targeted nanomedicines: principles and practice Lammers, T Hennink, W E Storm, G Br J Cancer Review Drug targeting systems are nanometre-sized carrier materials designed for improving the biodistribution of systemically applied (chemo)therapeutics. Various different tumour-targeted nanomedicines have been evaluated over the years, and clear evidence is currently available for substantial improvement of the therapeutic index of anticancer agents. Here, we briefly summarise the most important targeting systems and strategies, and discuss recent advances and future directions in the development of tumour-targeted nanomedicines. Nature Publishing Group 2008-08-05 2008-07-22 /pmc/articles/PMC2527811/ /pubmed/18648371 http://dx.doi.org/10.1038/sj.bjc.6604483 Text en Copyright © 2008 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Review
Lammers, T
Hennink, W E
Storm, G
Tumour-targeted nanomedicines: principles and practice
title Tumour-targeted nanomedicines: principles and practice
title_full Tumour-targeted nanomedicines: principles and practice
title_fullStr Tumour-targeted nanomedicines: principles and practice
title_full_unstemmed Tumour-targeted nanomedicines: principles and practice
title_short Tumour-targeted nanomedicines: principles and practice
title_sort tumour-targeted nanomedicines: principles and practice
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527811/
https://www.ncbi.nlm.nih.gov/pubmed/18648371
http://dx.doi.org/10.1038/sj.bjc.6604483
work_keys_str_mv AT lammerst tumourtargetednanomedicinesprinciplesandpractice
AT henninkwe tumourtargetednanomedicinesprinciplesandpractice
AT stormg tumourtargetednanomedicinesprinciplesandpractice

Ejemplares similares