Heterokaryon-Based Reprogramming of Human B Lymphocytes for Pluripotency Requires Oct4 but Not Sox2

Differentiated cells can be reprogrammed through the formation of heterokaryons and hybrid cells when fused with embryonic stem (ES) cells. Here, we provide evidence that conversion of human B-lymphocytes towards a multipotent state is initiated much more rapidly than previously thought, occurring i...

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Detalles Bibliográficos
Autores principales: Pereira, Carlos F., Terranova, Rémi, Ryan, Natalie K., Santos, Joana, Morris, Kelly J., Cui, Wei, Merkenschlager, Matthias, Fisher, Amanda G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527997/
https://www.ncbi.nlm.nih.gov/pubmed/18773085
http://dx.doi.org/10.1371/journal.pgen.1000170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527997/
https://www.ncbi.nlm.nih.gov/pubmed/18773085
http://dx.doi.org/10.1371/journal.pgen.1000170

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