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A Predominant Role for Parenchymal c-Jun Amino Terminal Kinase (JNK) in the Regulation of Systemic Insulin Sensitivity

It has been established that c-Jun N-terminal kinase 1 (JNK1) is essential to the pathogenesis of insulin resistance and type 2 diabetes. Although JNK influences inflammatory signaling pathways, it remains unclear whether its activity in macrophages contributes to adipose tissue inflammation and ult...

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Detalles Bibliográficos
Autores principales:	Vallerie, Sara N., Furuhashi, Masato, Fucho, Raquel, Hotamisligil, Gökhan S.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528001/ https://www.ncbi.nlm.nih.gov/pubmed/18773087 http://dx.doi.org/10.1371/journal.pone.0003151

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