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Occupational exposure to asbestos and mortality among asbestos removal workers: a Poisson regression analysis

The asbestos industry has shifted from manufacture to stripping/removal work. The aim of this study was to investigate early indications of mortality among removal workers. The study population consisted of 31 302 stripping/removal workers in the Great Britain Asbestos Survey, followed up to Decembe...

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Autores principales: Frost, G, Harding, A-H, Darnton, A, McElvenny, D, Morgan, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528146/
https://www.ncbi.nlm.nih.gov/pubmed/18728672
http://dx.doi.org/10.1038/sj.bjc.6604564
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author Frost, G
Harding, A-H
Darnton, A
McElvenny, D
Morgan, D
author_facet Frost, G
Harding, A-H
Darnton, A
McElvenny, D
Morgan, D
author_sort Frost, G
collection PubMed
description The asbestos industry has shifted from manufacture to stripping/removal work. The aim of this study was to investigate early indications of mortality among removal workers. The study population consisted of 31 302 stripping/removal workers in the Great Britain Asbestos Survey, followed up to December 2005. Relative risks (RR) for causes of death with elevated standardised mortality ratios (SMR) and sufficient deaths were obtained from Poisson regression. Risk factors considered included dust suppression technique, type of respirator used, hours spent stripping, smoking status and exposure length. Deaths were elevated for all causes (SMR 123, 95% CI 119–127, n=985), all cancers including lung cancer, mesothelioma, and circulatory disease. There were no significant differences between suppression techniques and respirator types. Spending more than 40 h per week stripping rather than less than 10, increased mortality risk from all causes (RR 1.4, 95% CI 1.2–1.7), circulatory disease and ischaemic heart disease. Elevated mesothelioma risks were observed for those first exposed at young ages or exposed for more than 30 years. This study is a first step in assessing long-term mortality of asbestos removal workers in relation to working practices and asbestos exposure. Further follow-up will allow the impact of recent regulations to be assessed.
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spelling pubmed-25281462009-09-11 Occupational exposure to asbestos and mortality among asbestos removal workers: a Poisson regression analysis Frost, G Harding, A-H Darnton, A McElvenny, D Morgan, D Br J Cancer Epidemiology The asbestos industry has shifted from manufacture to stripping/removal work. The aim of this study was to investigate early indications of mortality among removal workers. The study population consisted of 31 302 stripping/removal workers in the Great Britain Asbestos Survey, followed up to December 2005. Relative risks (RR) for causes of death with elevated standardised mortality ratios (SMR) and sufficient deaths were obtained from Poisson regression. Risk factors considered included dust suppression technique, type of respirator used, hours spent stripping, smoking status and exposure length. Deaths were elevated for all causes (SMR 123, 95% CI 119–127, n=985), all cancers including lung cancer, mesothelioma, and circulatory disease. There were no significant differences between suppression techniques and respirator types. Spending more than 40 h per week stripping rather than less than 10, increased mortality risk from all causes (RR 1.4, 95% CI 1.2–1.7), circulatory disease and ischaemic heart disease. Elevated mesothelioma risks were observed for those first exposed at young ages or exposed for more than 30 years. This study is a first step in assessing long-term mortality of asbestos removal workers in relation to working practices and asbestos exposure. Further follow-up will allow the impact of recent regulations to be assessed. Nature Publishing Group 2008-09-02 2008-08-19 /pmc/articles/PMC2528146/ /pubmed/18728672 http://dx.doi.org/10.1038/sj.bjc.6604564 Text en Copyright © 2008 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Epidemiology
Frost, G
Harding, A-H
Darnton, A
McElvenny, D
Morgan, D
Occupational exposure to asbestos and mortality among asbestos removal workers: a Poisson regression analysis
title Occupational exposure to asbestos and mortality among asbestos removal workers: a Poisson regression analysis
title_full Occupational exposure to asbestos and mortality among asbestos removal workers: a Poisson regression analysis
title_fullStr Occupational exposure to asbestos and mortality among asbestos removal workers: a Poisson regression analysis
title_full_unstemmed Occupational exposure to asbestos and mortality among asbestos removal workers: a Poisson regression analysis
title_short Occupational exposure to asbestos and mortality among asbestos removal workers: a Poisson regression analysis
title_sort occupational exposure to asbestos and mortality among asbestos removal workers: a poisson regression analysis
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528146/
https://www.ncbi.nlm.nih.gov/pubmed/18728672
http://dx.doi.org/10.1038/sj.bjc.6604564
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