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A phase II study of UFT with leucovorin administered as a twice daily schedule in the treatment of patients with metastatic colorectal cancer

Prolonged infusions have been shown to be safer and potentially more effective than bolus regimens of 5-fluorouracil (5-FU) as treatment for metastatic colorectal cancer (mCRC). However, infusional 5-FU requires central venous access and costly infusion pumps. Oral fluoropyrimidines enable longer ex...

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Detalles Bibliográficos
Autores principales:	Hoff, P M, Kopetz, S, Thomas, M B, Langleben, A, Rinaldi, D, Anthony, L, Wolff, R A, Lassere, Y, Abbruzzese, J L
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2008
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528148/ https://www.ncbi.nlm.nih.gov/pubmed/18728662 http://dx.doi.org/10.1038/sj.bjc.6604541

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