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The proofreading exonuclease subunit ε of Escherichia coli DNA polymerase III is tethered to the polymerase subunit α via a flexible linker

Escherichia coli DNA polymerase III holoenzyme is composed of 10 different subunits linked by noncovalent interactions. The polymerase activity resides in the α-subunit. The ε-subunit, which contains the proofreading exonuclease site within its N-terminal 185 residues, binds to α via a segment of 57...

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Detalles Bibliográficos
Autores principales:	Ozawa, Kiyoshi, Jergic, Slobodan, Park, Ah Young, Dixon, Nicholas E., Otting, Gottfried
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528190/ https://www.ncbi.nlm.nih.gov/pubmed/18663010 http://dx.doi.org/10.1093/nar/gkn489

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