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TLR ligand–induced podosome disassembly in dendritic cells is ADAM17 dependent
Toll-like receptor (TLR) signaling induces a rapid reorganization of the actin cytoskeleton in cultured mouse dendritic cells (DC), leading to enhanced antigen endocytosis and a concomitant loss of filamentous actin–rich podosomes. We show that as podosomes are lost, TLR signaling induces prominent...
Autores principales: | West, Michele A., Prescott, Alan R., Chan, Kui Ming, Zhou, Zhongjun, Rose-John, Stefan, Scheller, Jürgen, Watts, Colin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528573/ https://www.ncbi.nlm.nih.gov/pubmed/18762577 http://dx.doi.org/10.1083/jcb.200801022 |
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