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MTOC translocation modulates IS formation and controls sustained T cell signaling

The translocation of the microtubule-organizing center (MTOC) toward the nascent immune synapse (IS) is an early step in lymphocyte activation initiated by T cell receptor (TCR) signaling. The molecular mechanisms that control the physical movement of the lymphocyte MTOC remain largely unknown. We h...

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Detalles Bibliográficos
Autores principales:	Martín-Cófreces, Noa B., Robles-Valero, Javier, Cabrero, J. Román, Mittelbrunn, María, Gordón-Alonso, Mónica, Sung, Ching-Hwa, Alarcón, Balbino, Vázquez, Jesús, Sánchez-Madrid, Francisco
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528574/ https://www.ncbi.nlm.nih.gov/pubmed/18779373 http://dx.doi.org/10.1083/jcb.200801014

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