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A Dual Receptor Crosstalk Model of G-Protein-Coupled Signal Transduction
Macrophage cells that are stimulated by two different ligands that bind to G-protein-coupled receptors (GPCRs) usually respond as if the stimulus effects are additive, but for a minority of ligand combinations the response is synergistic. The G-protein-coupled receptor system integrates signaling cu...
Autores principales: | Flaherty, Patrick, Radhakrishnan, Mala L., Dinh, Tuan, Rebres, Robert A., Roach, Tamara I., Jordan, Michael I., Arkin, Adam P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528964/ https://www.ncbi.nlm.nih.gov/pubmed/18818727 http://dx.doi.org/10.1371/journal.pcbi.1000185 |
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