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Complex I within Oxidatively Stressed Bovine Heart Mitochondria Is Glutathionylated on Cys-531 and Cys-704 of the 75-kDa Subunit: POTENTIAL ROLE OF CYS RESIDUES IN DECREASING OXIDATIVE DAMAGE

Complex I has reactive thiols on its surface that interact with the mitochondrial glutathione pool and are implicated in oxidative damage in many pathologies. However, the Cys residues and the thiol modifications involved are not known. Here we investigate complex I thiol modification within oxidati...

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Detalles Bibliográficos
Autores principales:	Hurd, Thomas R., Requejo, Raquel, Filipovska, Aleksandra, Brown, Stephanie, Prime, Tracy A., Robinson, Alan J., Fearnley, Ian M., Murphy, Michael P.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Metabolism and Bioenergetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529008/ https://www.ncbi.nlm.nih.gov/pubmed/18611857 http://dx.doi.org/10.1074/jbc.M803432200

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