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Integrative analysis of RUNX1 downstream pathways and target genes
BACKGROUND: The RUNX1 transcription factor gene is frequently mutated in sporadic myeloid and lymphoid leukemia through translocation, point mutation or amplification. It is also responsible for a familial platelet disorder with predisposition to acute myeloid leukemia (FPD-AML). The disruption of t...
Autores principales: | Michaud, Joëlle, Simpson, Ken M, Escher, Robert, Buchet-Poyau, Karine, Beissbarth, Tim, Carmichael, Catherine, Ritchie, Matthew E, Schütz, Frédéric, Cannon, Ping, Liu, Marjorie, Shen, Xiaofeng, Ito, Yoshiaki, Raskind, Wendy H, Horwitz, Marshall S, Osato, Motomi, Turner, David R, Speed, Terence P, Kavallaris, Maria, Smyth, Gordon K, Scott, Hamish S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529319/ https://www.ncbi.nlm.nih.gov/pubmed/18671852 http://dx.doi.org/10.1186/1471-2164-9-363 |
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