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Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands

BACKGROUND: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role in tumor development, CpG island methylation contributes to the acquisition of resistance to chemotherapy. Differential...

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Detalles Bibliográficos
Autores principales:	Dai, Wei, Teodoridis, Jens M, Graham, Janet, Zeller, Constanze, Huang, Tim HM, Yan, Pearlly, Vass, J Keith, Brown, Robert, Paul, Jim
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529322/ https://www.ncbi.nlm.nih.gov/pubmed/18691414 http://dx.doi.org/10.1186/1471-2105-9-337

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