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[(11)C]CHIBA-1001 as a Novel PET Ligand for α7 Nicotinic Receptors in the Brain: A PET Study in Conscious Monkeys

BACKGROUND: The α7 nicotinic acetylcholine receptors (nAChRs) play an important role in the pathophysiology of neuropsychiatric diseases such as schizophrenia and Alzheimer's disease. However, there are currently no suitable positron emission tomography (PET) radioligands for imaging α7 nAChRs...

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Detalles Bibliográficos
Autores principales:	Hashimoto, Kenji, Nishiyama, Shingo, Ohba, Hiroyuki, Matsuo, Masaaki, Kobashi, Tatsuhiko, Takahagi, Makoto, Iyo, Masaomi, Kitashoji, Takeru, Tsukada, Hideo
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529405/ https://www.ncbi.nlm.nih.gov/pubmed/18800169 http://dx.doi.org/10.1371/journal.pone.0003231

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