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MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization

Summary: We present MetaRoute, an efficient search algorithm based on atom mapping rules and path weighting schemes that returns relevant or textbook-like routes between a source and a product metabolite within seconds for genome-scale networks. Its speed allows the algorithm to be used interactivel...

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Detalles Bibliográficos
Autores principales: Blum, Torsten, Kohlbacher, Oliver
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2530881/
https://www.ncbi.nlm.nih.gov/pubmed/18635573
http://dx.doi.org/10.1093/bioinformatics/btn360
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author Blum, Torsten
Kohlbacher, Oliver
author_facet Blum, Torsten
Kohlbacher, Oliver
author_sort Blum, Torsten
collection PubMed
description Summary: We present MetaRoute, an efficient search algorithm based on atom mapping rules and path weighting schemes that returns relevant or textbook-like routes between a source and a product metabolite within seconds for genome-scale networks. Its speed allows the algorithm to be used interactively through a web interface to visualize relevant routes and local networks for one or multiple organisms based on data from KEGG. Availability: http://www-bs.informatik.uni-tuebingen.de/Services/MetaRoute. Contact: blum@informatik.uni-tuebingen.de Supplementary information: Supplementary details are available at http://www-bs.informatik.uni-tuebingen.de/Services/MetaRoute
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spelling pubmed-25308812009-02-25 MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization Blum, Torsten Kohlbacher, Oliver Bioinformatics Applications Note Summary: We present MetaRoute, an efficient search algorithm based on atom mapping rules and path weighting schemes that returns relevant or textbook-like routes between a source and a product metabolite within seconds for genome-scale networks. Its speed allows the algorithm to be used interactively through a web interface to visualize relevant routes and local networks for one or multiple organisms based on data from KEGG. Availability: http://www-bs.informatik.uni-tuebingen.de/Services/MetaRoute. Contact: blum@informatik.uni-tuebingen.de Supplementary information: Supplementary details are available at http://www-bs.informatik.uni-tuebingen.de/Services/MetaRoute Oxford University Press 2008-09-15 2008-07-16 /pmc/articles/PMC2530881/ /pubmed/18635573 http://dx.doi.org/10.1093/bioinformatics/btn360 Text en © 2008 The Author(s) http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Note
Blum, Torsten
Kohlbacher, Oliver
MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization
title MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization
title_full MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization
title_fullStr MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization
title_full_unstemmed MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization
title_short MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization
title_sort metaroute: fast search for relevant metabolic routes for interactive network navigation and visualization
topic Applications Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2530881/
https://www.ncbi.nlm.nih.gov/pubmed/18635573
http://dx.doi.org/10.1093/bioinformatics/btn360
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