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Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature

Deaths after percutaneous ethanol injection (PEI) into hepatocellular carcinoma (HCC) may occur within a few hours to a few days following the procedure because of hemoperitoneum and haemorrhage from oesophageal varices or hepatic insufficiency. Pancreatitis has been recently reported as a rare leth...

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Autores principales: Zardi, Enrico M, Di Matteo, Francesco, Santini, Daniele, Uwechie, Valentina, Crucitti, Pierfilippo, Carassiti, Massimiliano, Picardi, Antonio, Perrella, Eleonora, Caricato, Marco, Tonini, Giuseppe, Coppola, Roberto, Afeltra, Antonella
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2531081/
https://www.ncbi.nlm.nih.gov/pubmed/18702805
http://dx.doi.org/10.1186/1756-9966-27-28
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author Zardi, Enrico M
Di Matteo, Francesco
Santini, Daniele
Uwechie, Valentina
Crucitti, Pierfilippo
Carassiti, Massimiliano
Picardi, Antonio
Perrella, Eleonora
Caricato, Marco
Tonini, Giuseppe
Coppola, Roberto
Afeltra, Antonella
author_facet Zardi, Enrico M
Di Matteo, Francesco
Santini, Daniele
Uwechie, Valentina
Crucitti, Pierfilippo
Carassiti, Massimiliano
Picardi, Antonio
Perrella, Eleonora
Caricato, Marco
Tonini, Giuseppe
Coppola, Roberto
Afeltra, Antonella
author_sort Zardi, Enrico M
collection PubMed
description Deaths after percutaneous ethanol injection (PEI) into hepatocellular carcinoma (HCC) may occur within a few hours to a few days following the procedure because of hemoperitoneum and haemorrhage from oesophageal varices or hepatic insufficiency. Pancreatitis has been recently reported as a rare lethal complication of intra-arterial PEI, another modality for treating HCCs. In this minireview, we analyze the literature concerning the development of acute pancreatitis after PEI. Pathogenesis of pancreatitis from opioids and ethanol is also addressed. Treatment with opioids to reduce the patient's abdominal pain after PEI in combination with the PEI itself may lead to direct toxic effects, thus favouring the development of pancreatitis.
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spelling pubmed-25310812008-09-06 Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature Zardi, Enrico M Di Matteo, Francesco Santini, Daniele Uwechie, Valentina Crucitti, Pierfilippo Carassiti, Massimiliano Picardi, Antonio Perrella, Eleonora Caricato, Marco Tonini, Giuseppe Coppola, Roberto Afeltra, Antonella J Exp Clin Cancer Res Review Deaths after percutaneous ethanol injection (PEI) into hepatocellular carcinoma (HCC) may occur within a few hours to a few days following the procedure because of hemoperitoneum and haemorrhage from oesophageal varices or hepatic insufficiency. Pancreatitis has been recently reported as a rare lethal complication of intra-arterial PEI, another modality for treating HCCs. In this minireview, we analyze the literature concerning the development of acute pancreatitis after PEI. Pathogenesis of pancreatitis from opioids and ethanol is also addressed. Treatment with opioids to reduce the patient's abdominal pain after PEI in combination with the PEI itself may lead to direct toxic effects, thus favouring the development of pancreatitis. BioMed Central 2008-08-14 /pmc/articles/PMC2531081/ /pubmed/18702805 http://dx.doi.org/10.1186/1756-9966-27-28 Text en Copyright © 2008 Zardi et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Zardi, Enrico M
Di Matteo, Francesco
Santini, Daniele
Uwechie, Valentina
Crucitti, Pierfilippo
Carassiti, Massimiliano
Picardi, Antonio
Perrella, Eleonora
Caricato, Marco
Tonini, Giuseppe
Coppola, Roberto
Afeltra, Antonella
Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature
title Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature
title_full Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature
title_fullStr Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature
title_full_unstemmed Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature
title_short Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature
title_sort pancreatitis after percutaneous ethanol injection into hcc: a minireview of the literature
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2531081/
https://www.ncbi.nlm.nih.gov/pubmed/18702805
http://dx.doi.org/10.1186/1756-9966-27-28
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