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Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature
Deaths after percutaneous ethanol injection (PEI) into hepatocellular carcinoma (HCC) may occur within a few hours to a few days following the procedure because of hemoperitoneum and haemorrhage from oesophageal varices or hepatic insufficiency. Pancreatitis has been recently reported as a rare leth...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2531081/ https://www.ncbi.nlm.nih.gov/pubmed/18702805 http://dx.doi.org/10.1186/1756-9966-27-28 |
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author | Zardi, Enrico M Di Matteo, Francesco Santini, Daniele Uwechie, Valentina Crucitti, Pierfilippo Carassiti, Massimiliano Picardi, Antonio Perrella, Eleonora Caricato, Marco Tonini, Giuseppe Coppola, Roberto Afeltra, Antonella |
author_facet | Zardi, Enrico M Di Matteo, Francesco Santini, Daniele Uwechie, Valentina Crucitti, Pierfilippo Carassiti, Massimiliano Picardi, Antonio Perrella, Eleonora Caricato, Marco Tonini, Giuseppe Coppola, Roberto Afeltra, Antonella |
author_sort | Zardi, Enrico M |
collection | PubMed |
description | Deaths after percutaneous ethanol injection (PEI) into hepatocellular carcinoma (HCC) may occur within a few hours to a few days following the procedure because of hemoperitoneum and haemorrhage from oesophageal varices or hepatic insufficiency. Pancreatitis has been recently reported as a rare lethal complication of intra-arterial PEI, another modality for treating HCCs. In this minireview, we analyze the literature concerning the development of acute pancreatitis after PEI. Pathogenesis of pancreatitis from opioids and ethanol is also addressed. Treatment with opioids to reduce the patient's abdominal pain after PEI in combination with the PEI itself may lead to direct toxic effects, thus favouring the development of pancreatitis. |
format | Text |
id | pubmed-2531081 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-25310812008-09-06 Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature Zardi, Enrico M Di Matteo, Francesco Santini, Daniele Uwechie, Valentina Crucitti, Pierfilippo Carassiti, Massimiliano Picardi, Antonio Perrella, Eleonora Caricato, Marco Tonini, Giuseppe Coppola, Roberto Afeltra, Antonella J Exp Clin Cancer Res Review Deaths after percutaneous ethanol injection (PEI) into hepatocellular carcinoma (HCC) may occur within a few hours to a few days following the procedure because of hemoperitoneum and haemorrhage from oesophageal varices or hepatic insufficiency. Pancreatitis has been recently reported as a rare lethal complication of intra-arterial PEI, another modality for treating HCCs. In this minireview, we analyze the literature concerning the development of acute pancreatitis after PEI. Pathogenesis of pancreatitis from opioids and ethanol is also addressed. Treatment with opioids to reduce the patient's abdominal pain after PEI in combination with the PEI itself may lead to direct toxic effects, thus favouring the development of pancreatitis. BioMed Central 2008-08-14 /pmc/articles/PMC2531081/ /pubmed/18702805 http://dx.doi.org/10.1186/1756-9966-27-28 Text en Copyright © 2008 Zardi et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Zardi, Enrico M Di Matteo, Francesco Santini, Daniele Uwechie, Valentina Crucitti, Pierfilippo Carassiti, Massimiliano Picardi, Antonio Perrella, Eleonora Caricato, Marco Tonini, Giuseppe Coppola, Roberto Afeltra, Antonella Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature |
title | Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature |
title_full | Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature |
title_fullStr | Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature |
title_full_unstemmed | Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature |
title_short | Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature |
title_sort | pancreatitis after percutaneous ethanol injection into hcc: a minireview of the literature |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2531081/ https://www.ncbi.nlm.nih.gov/pubmed/18702805 http://dx.doi.org/10.1186/1756-9966-27-28 |
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