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A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development
BACKGROUND: The alarming rise in the obesity epidemic and growing concern for the pathologic consequences of the metabolic syndrome warrant great need for development of obesity-related pharmacotherapeutics. The search for such therapeutics is severely limited by the slow throughput of animal models...
Autores principales: | Jones, Kevin S, Alimov, Alexander P, Rilo, Horacio L, Jandacek, Ronald J, Woollett, Laura A, Penberthy, W Todd |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2531115/ https://www.ncbi.nlm.nih.gov/pubmed/18752667 http://dx.doi.org/10.1186/1743-7075-5-23 |
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