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Chemogenetic fingerprinting by analysis of cellular growth dynamics

BACKGROUND: A fundamental goal in chemical biology is the elucidation of on- and off-target effects of drugs and biocides. To this aim chemogenetic screens that quantify drug induced changes in cellular fitness, typically taken as changes in composite growth, is commonly applied. RESULTS: Using the...

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Detalles Bibliográficos
Autores principales: Warringer, Jonas, Anevski, Dragi, Liu, Beidong, Blomberg, Anders
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532679/
https://www.ncbi.nlm.nih.gov/pubmed/18721464
http://dx.doi.org/10.1186/1472-6769-8-3