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Analysis of the piggyBac transposase reveals a functional nuclear targeting signal in the 94 c-terminal residues

BACKGROUND: The piggyBac transposable element is a popular tool for germ-line transgenesis of eukaryotes. Despite this, little is known about the mechanism of transposition or the transposase (TPase) itself. A thorough understanding of just how piggyBac works may lead to more effective use of this i...

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Detalles Bibliográficos
Autores principales: Keith, James H, Fraser, Tresa S, Fraser, Malcolm J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532691/
https://www.ncbi.nlm.nih.gov/pubmed/18694511
http://dx.doi.org/10.1186/1471-2199-9-72

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