Identification of a novel CHEK2 variant and assessment of its contribution to the risk of breast cancer in French Canadian women

BACKGROUND: BRCA1 and BRCA2 account for the majority of the known familial breast cancer risk, however, the impact of other cancer susceptibility genes largely remains to be elucidated. Checkpoint Kinase 2 (CHEK2) is an important signal transducer of cellular responses to DNA damage, whose defects h...

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Detalles Bibliográficos
Autores principales: Novak, David J, Chen, Long Qi, Ghadirian, Parviz, Hamel, Nancy, Zhang, Phil, Rossiny, Vanessa, Cardinal, Guy, Robidoux, André, Tonin, Patricia N, Rousseau, Francois, Narod, Steven A, Foulkes, William D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532692/
https://www.ncbi.nlm.nih.gov/pubmed/18706089
http://dx.doi.org/10.1186/1471-2407-8-239

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