The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase δ

Bloom's syndrome (BS) is a cancer predisposition disorder caused by mutation of the BLM gene, encoding a member of the RecQ helicase family. Although the phenotype of BS cells is suggestive of a role for BLM in repair of stalled or damaged replication forks, thus far there has been no direct ev...

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Detalles Bibliográficos
Autores principales: Selak, Nives, Bachrati, Csanád Z., Shevelev, Igor, Dietschy, Tobias, van Loon, Barbara, Jacob, Anette, Hübscher, Ulrich, Hoheisel, Joerg D., Hickson, Ian D., Stagljar, Igor
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532730/
https://www.ncbi.nlm.nih.gov/pubmed/18682526
http://dx.doi.org/10.1093/nar/gkn498

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