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Hyperthermophilic Aquifex aeolicus initiates primer synthesis on a limited set of trinucleotides comprised of cytosines and guanines

The placement of the extreme thermophile Aquifex aeolicus in the bacterial phylogenetic tree has evoked much controversy. We investigated whether adaptations for growth at high temperatures would alter a key functional component of the replication machinery, specifically DnaG primase. Although the s...

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Detalles Bibliográficos
Autores principales:	Larson, Marilynn A., Bressani, Rafael, Sayood, Khalid, Corn, Jacob E., Berger, James M., Griep, Mark A., Hinrichs, Steven H.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532735/ https://www.ncbi.nlm.nih.gov/pubmed/18684998 http://dx.doi.org/10.1093/nar/gkn461

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