A functional genome-wide RNAi screen identifies TAF1 as a regulator for apoptosis in response to genotoxic stress

Evasion from apoptotic cell death is a characteristic of cancer; genes that modulate this process may be optimal for therapeutic attack. Identifying key regulators of apoptosis is thus a central goal in cancer therapy. Here, we describe a loss-of-function screen that uses RNA interference libraries...

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Detalles Bibliográficos
Autores principales: Kimura, Junko, Nguyen, Su Tien, Liu, Hanshao, Taira, Naoe, Miki, Yoshio, Yoshida, Kiyotsugu
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532742/
https://www.ncbi.nlm.nih.gov/pubmed/18684994
http://dx.doi.org/10.1093/nar/gkn506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532742/
https://www.ncbi.nlm.nih.gov/pubmed/18684994
http://dx.doi.org/10.1093/nar/gkn506

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