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A functional genome-wide RNAi screen identifies TAF1 as a regulator for apoptosis in response to genotoxic stress
Evasion from apoptotic cell death is a characteristic of cancer; genes that modulate this process may be optimal for therapeutic attack. Identifying key regulators of apoptosis is thus a central goal in cancer therapy. Here, we describe a loss-of-function screen that uses RNA interference libraries...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532742/ https://www.ncbi.nlm.nih.gov/pubmed/18684994 http://dx.doi.org/10.1093/nar/gkn506 |