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Somatic ‘Soluble’ Adenylyl Cyclase Isoforms Are Unaffected in Sacy(tm1Lex)/Sacy(tm1Lex) ‘Knockout’ Mice
BACKGROUND: Mammalian Soluble adenylyl cyclase (sAC, Adcy10, or Sacy) represents a source of the second messenger cAMP distinct from the widely studied, G protein-regulated transmembrane adenylyl cyclases. Genetic deletion of the second through fourth coding exons in Sacy(tm1Lex)/Sacy(tm1Lex) knocko...
Autores principales: | Farrell, Jeanne, Ramos, Lavoisier, Tresguerres, Martin, Kamenetsky, Margarita, Levin, Lonny R., Buck, Jochen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532759/ https://www.ncbi.nlm.nih.gov/pubmed/18806876 http://dx.doi.org/10.1371/journal.pone.0003251 |
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