SIRT3 interacts with the daf-16 homolog FOXO3a in the Mitochondria, as well as increases FOXO3a Dependent Gene expression

Cellular longevity is a complex process relevant to age-related diseases including but not limited to chronic illness such as diabetes and metabolic syndromes. Two gene families have been shown to play a role in the genetic regulation of longevity; the Sirtuin and FOXO families. It is also establish...

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Detalles Bibliográficos
Autores principales: Jacobs, Kristi Muldoon, Pennington, J. Daniel, Bisht, Kheem S., Aykin-Burns, Nukhet, Kim, Hyun-Seok, Mishra, Mark, Sun, Lunching, Nguyen, Phuongmai, Ahn, Bong-Hyun, Leclerc, Jaime, Deng, Chu-Xia, Spitz, Douglas R., Gius, David
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2008
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532794/
https://www.ncbi.nlm.nih.gov/pubmed/18781224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532794/
https://www.ncbi.nlm.nih.gov/pubmed/18781224

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