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Testing for allergic disease: Parameters considered and test value

BACKGROUND: Test results for allergic disease are especially valuable to allergists and family physicians for clinical evaluation, decisions to treat, and to determine needs for referral. METHODS: This study used a repeated measures design (conjoint analysis) to examine trade offs among clinical par...

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Autores principales: Szeinbach, Sheryl L, Harpe, Spencer E, Williams, P Brock, Elhefni, Hanaa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532998/
https://www.ncbi.nlm.nih.gov/pubmed/18727827
http://dx.doi.org/10.1186/1471-2296-9-47
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author Szeinbach, Sheryl L
Harpe, Spencer E
Williams, P Brock
Elhefni, Hanaa
author_facet Szeinbach, Sheryl L
Harpe, Spencer E
Williams, P Brock
Elhefni, Hanaa
author_sort Szeinbach, Sheryl L
collection PubMed
description BACKGROUND: Test results for allergic disease are especially valuable to allergists and family physicians for clinical evaluation, decisions to treat, and to determine needs for referral. METHODS: This study used a repeated measures design (conjoint analysis) to examine trade offs among clinical parameters that influence the decision of family physicians to use specific IgE blood testing as a diagnostic aid for patients suspected of having allergic rhinitis. Data were extracted from a random sample of 50 family physicians in the Southeastern United States. Physicians evaluated 11 patient profiles containing four clinical parameters: symptom severity (low, medium, high), symptom length (5, 10, 20 years), family history (both parents, mother, neither), and medication use (prescribed antihistamines, nasal spray, over-the-counter medications). Decision to recommend specific IgE testing was elicited as a "yes" or "no" response. Perceived value of specific IgE blood testing was evaluated according to usefulness as a diagnostic tool compared to skin testing, and not testing. RESULTS: The highest odds ratios (OR) associated with decisions to test for allergic rhinitis were obtained for symptom severity (OR, 12.11; 95%CI, 7.1–20.7) and length of symptoms (OR, 1.46; 95%CI, 0.96–2.2) with family history having significant influence in the decision. A moderately positive association between testing issues and testing value was revealed (β = 0.624, t = 5.296, p ≤ 0.001) with 39% of the variance explained by the regression model. CONCLUSION: The most important parameters considered when testing for allergic rhinitis relate to symptom severity, length of symptoms, and family history. Family physicians recognize that specific IgE blood testing is valuable to their practice.
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spelling pubmed-25329982008-09-10 Testing for allergic disease: Parameters considered and test value Szeinbach, Sheryl L Harpe, Spencer E Williams, P Brock Elhefni, Hanaa BMC Fam Pract Research Article BACKGROUND: Test results for allergic disease are especially valuable to allergists and family physicians for clinical evaluation, decisions to treat, and to determine needs for referral. METHODS: This study used a repeated measures design (conjoint analysis) to examine trade offs among clinical parameters that influence the decision of family physicians to use specific IgE blood testing as a diagnostic aid for patients suspected of having allergic rhinitis. Data were extracted from a random sample of 50 family physicians in the Southeastern United States. Physicians evaluated 11 patient profiles containing four clinical parameters: symptom severity (low, medium, high), symptom length (5, 10, 20 years), family history (both parents, mother, neither), and medication use (prescribed antihistamines, nasal spray, over-the-counter medications). Decision to recommend specific IgE testing was elicited as a "yes" or "no" response. Perceived value of specific IgE blood testing was evaluated according to usefulness as a diagnostic tool compared to skin testing, and not testing. RESULTS: The highest odds ratios (OR) associated with decisions to test for allergic rhinitis were obtained for symptom severity (OR, 12.11; 95%CI, 7.1–20.7) and length of symptoms (OR, 1.46; 95%CI, 0.96–2.2) with family history having significant influence in the decision. A moderately positive association between testing issues and testing value was revealed (β = 0.624, t = 5.296, p ≤ 0.001) with 39% of the variance explained by the regression model. CONCLUSION: The most important parameters considered when testing for allergic rhinitis relate to symptom severity, length of symptoms, and family history. Family physicians recognize that specific IgE blood testing is valuable to their practice. BioMed Central 2008-08-26 /pmc/articles/PMC2532998/ /pubmed/18727827 http://dx.doi.org/10.1186/1471-2296-9-47 Text en Copyright © 2008 Szeinbach et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Szeinbach, Sheryl L
Harpe, Spencer E
Williams, P Brock
Elhefni, Hanaa
Testing for allergic disease: Parameters considered and test value
title Testing for allergic disease: Parameters considered and test value
title_full Testing for allergic disease: Parameters considered and test value
title_fullStr Testing for allergic disease: Parameters considered and test value
title_full_unstemmed Testing for allergic disease: Parameters considered and test value
title_short Testing for allergic disease: Parameters considered and test value
title_sort testing for allergic disease: parameters considered and test value
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532998/
https://www.ncbi.nlm.nih.gov/pubmed/18727827
http://dx.doi.org/10.1186/1471-2296-9-47
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