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Roles of PI3K and JAK pathways in viability of retinal ganglion cells after acute elevation of intraocular pressure in rats with different autoimmune backgrounds

BACKGROUND: We recently showed that whereas inhibition of PI3K/akt or JAK/STAT pathway promoted retinal ganglion cell (RGC) survival after optic nerve (ON) injury in Fischer 344 (F344) rats, the same inhibition resulted in aggravated RGC loss after acute intraocular pressure (IOP) elevation in Sprag...

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Detalles Bibliográficos
Autores principales:	Huang, Yao, Li, Zhiwei, Wang, Ningli, van Rooijen, Nico, Cui, Qi
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533008/ https://www.ncbi.nlm.nih.gov/pubmed/18691439 http://dx.doi.org/10.1186/1471-2202-9-78

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