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Roles of PI3K and JAK pathways in viability of retinal ganglion cells after acute elevation of intraocular pressure in rats with different autoimmune backgrounds
BACKGROUND: We recently showed that whereas inhibition of PI3K/akt or JAK/STAT pathway promoted retinal ganglion cell (RGC) survival after optic nerve (ON) injury in Fischer 344 (F344) rats, the same inhibition resulted in aggravated RGC loss after acute intraocular pressure (IOP) elevation in Sprag...
Autores principales: | Huang, Yao, Li, Zhiwei, Wang, Ningli, van Rooijen, Nico, Cui, Qi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533008/ https://www.ncbi.nlm.nih.gov/pubmed/18691439 http://dx.doi.org/10.1186/1471-2202-9-78 |
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