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Differential expression of the TFIIIB subunits Brf1 and Brf2 in cancer cells
BACKGROUND: RNA polymerase (pol) III transcription is specifically elevated in a variety of cancers and is a target of regulation by a variety of tumor suppressors and oncogenes. Accurate initiation by RNA pol III is dependent on TFIIIB. In higher eukaryotes, two forms of TFIIIB have been characteri...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533013/ https://www.ncbi.nlm.nih.gov/pubmed/18700021 http://dx.doi.org/10.1186/1471-2199-9-74 |