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Differential expression of the TFIIIB subunits Brf1 and Brf2 in cancer cells

BACKGROUND: RNA polymerase (pol) III transcription is specifically elevated in a variety of cancers and is a target of regulation by a variety of tumor suppressors and oncogenes. Accurate initiation by RNA pol III is dependent on TFIIIB. In higher eukaryotes, two forms of TFIIIB have been characteri...

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Detalles Bibliográficos
Autores principales: Cabarcas, Stephanie, Jacob, Joby, Veras, Ingrid, Schramm, Laura
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533013/
https://www.ncbi.nlm.nih.gov/pubmed/18700021
http://dx.doi.org/10.1186/1471-2199-9-74