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Novel functional view of the crocidolite asbestos-treated A549 human lung epithelial transcriptome reveals an intricate network of pathways with opposing functions

BACKGROUND: Although exposure to asbestos is now regulated, patients continue to be diagnosed with mesothelioma, asbestosis, fibrosis and lung carcinoma because of the long latent period between exposure and clinical disease. Asbestosis is observed in approximately 200,000 patients annually and asbe...

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Detalles Bibliográficos
Autores principales: Hevel, Joan M, Olson-Buelow, Laura C, Ganesan, Balasubramanian, Stevens, John R, Hardman, Jared P, Aust, Ann E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533023/
https://www.ncbi.nlm.nih.gov/pubmed/18687144
http://dx.doi.org/10.1186/1471-2164-9-376