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Enhanced Glucose Requirement in Human Hepatoma-derived HuH-7 Cells by Forced Expression of the bcl-2 Gene

To explore the metabolic effects of Bcl-2 in tumor cells, a stable clone of HuH-7/bcl-2 and its control HuH-7/neo were established. Mitochondrial localization of ectopic Bcl-2 was demonstrated both by western blotting and immunofluorescence. HuH-7/bcl-2 cells consumed glucose at a higher rate, exhau...

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Detalles Bibliográficos
Autores principales: Okamoto, Kyoko, Muraguchi, Takashi, Shidoji, Yoshihiro
Formato: Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533714/
https://www.ncbi.nlm.nih.gov/pubmed/18818743
http://dx.doi.org/10.3164/jcbn.2008053

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