APOBEC3G-UBA2 fusion as a potential strategy for stable expression of APOBEC3G and inhibition of HIV-1 replication

BACKGROUND: Although APOBEC3G protein is a potent and innate anti-HIV-1 cellular factor, HIV-1 Vif counteracts the effect of APOBEC3G by promoting its degradation through proteasome-mediated proteolysis. Thus, any means that could prevent APOBEC3G degradation could potentially enhance its anti-viral...

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Detalles Bibliográficos
Autores principales: Li, Lin, Liang, Dong, Li, Jing-yun, Zhao, Richard Y
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535603/
https://www.ncbi.nlm.nih.gov/pubmed/18680593
http://dx.doi.org/10.1186/1742-4690-5-72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535603/
https://www.ncbi.nlm.nih.gov/pubmed/18680593
http://dx.doi.org/10.1186/1742-4690-5-72

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