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Getting a Transcription Factor to Only One Nucleus Following Mitosis

The Ace2 transcription factor from budding yeast has both a regulated nuclear localization signal and a regulated nuclear export signal, and Ace2 phosphorylation by the Cbk1 kinase results in Ace2 accumulation in daughter cells but not mothers.

Detalles Bibliográficos
Autores principales: Parnell, Emily J, Stillman, David J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535661/
https://www.ncbi.nlm.nih.gov/pubmed/18798694
http://dx.doi.org/10.1371/journal.pbio.0060229
Descripción
Sumario:The Ace2 transcription factor from budding yeast has both a regulated nuclear localization signal and a regulated nuclear export signal, and Ace2 phosphorylation by the Cbk1 kinase results in Ace2 accumulation in daughter cells but not mothers.