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Use of latent class models to accommodate inter-laboratory variation in assessing genetic polymorphisms associated with disease risk

BACKGROUND: Researchers wanting to study the association of genetic factors with disease may encounter variability in the laboratory methods used to establish genotypes or other traits. Such variability leads to uncertainty in determining the strength of a genotype as a risk factor. This problem is...

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Detalles Bibliográficos
Autores principales: Walter, Stephen D, Franco, Eduardo L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2536667/
https://www.ncbi.nlm.nih.gov/pubmed/18691419
http://dx.doi.org/10.1186/1471-2156-9-51