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Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas

BACKGROUND: Glioblastoma is the most lethal primary malignant brain tumor. Although considerable progress has been made in the treatment of this aggressive tumor, the clinical outcome for patients remains poor. Histone deacetylases (HDACs) are recognized as promising targets for cancer treatment. In...

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Detalles Bibliográficos
Autores principales:	Lucio-Eterovic, Agda KB, Cortez, Maria AA, Valera, Elvis T, Motta, Fabio JN, Queiroz, Rosane GP, Machado, Helio R, Carlotti, Carlos G, Neder, Luciano, Scrideli, Carlos A, Tone, Luiz G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2536671/ https://www.ncbi.nlm.nih.gov/pubmed/18713462 http://dx.doi.org/10.1186/1471-2407-8-243

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