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Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle
We determined the effects of intravenous infusion of amino acids (AA) at serum insulin of 5, 30, 72, and 167 mU/l on anabolic signaling, expression of ubiquitin-proteasome components, and protein turnover in muscles of healthy young men. Tripling AA availability at 5 mU/l insulin doubled incorporati...
Autores principales: | Greenhaff, P. L., Karagounis, L. G., Peirce, N., Simpson, E. J., Hazell, M., Layfield, R., Wackerhage, H., Smith, K., Atherton, P., Selby, A., Rennie, M. J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2536736/ https://www.ncbi.nlm.nih.gov/pubmed/18577697 http://dx.doi.org/10.1152/ajpendo.90411.2008 |
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