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Tracing Sub-Structure in the European American Population with PCA-Informative Markers
Genetic structure in the European American population reflects waves of migration and recent gene flow among different populations. This complex structure can introduce bias in genetic association studies. Using Principal Components Analysis (PCA), we analyze the structure of two independent Europea...
Autores principales: | Paschou, Peristera, Drineas, Petros, Lewis, Jamey, Nievergelt, Caroline M., Nickerson, Deborah A., Smith, Joshua D., Ridker, Paul M., Chasman, Daniel I., Krauss, Ronald M., Ziv, Elad |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2537989/ https://www.ncbi.nlm.nih.gov/pubmed/18797516 http://dx.doi.org/10.1371/journal.pgen.1000114 |
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