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Tracing Sub-Structure in the European American Population with PCA-Informative Markers

Genetic structure in the European American population reflects waves of migration and recent gene flow among different populations. This complex structure can introduce bias in genetic association studies. Using Principal Components Analysis (PCA), we analyze the structure of two independent Europea...

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Detalles Bibliográficos
Autores principales: Paschou, Peristera, Drineas, Petros, Lewis, Jamey, Nievergelt, Caroline M., Nickerson, Deborah A., Smith, Joshua D., Ridker, Paul M., Chasman, Daniel I., Krauss, Ronald M., Ziv, Elad
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2537989/
https://www.ncbi.nlm.nih.gov/pubmed/18797516
http://dx.doi.org/10.1371/journal.pgen.1000114

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