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HIV-1 with Multiple CCR5/CXCR4 Chimeric Receptor Use Is Predictive of Immunological Failure in Infected Children

BACKGROUND: HIV-1 R5 viruses are characterized by a large phenotypic variation, that is reflected by the mode of coreceptor use. The ability of R5 HIV-1 to infect target cells expressing chimeric receptors between CCR5 and CXCR4 (R5(broad) viruses), was shown to correlate with disease stage in HIV-1...

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Detalles Bibliográficos
Autores principales:	Cavarelli, Mariangela, Karlsson, Ingrid, Zanchetta, Marisa, Antonsson, Liselotte, Plebani, Anna, Giaquinto, Carlo, Fenyö, Eva Maria, De Rossi, Anita, Scarlatti, Gabriella
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538568/ https://www.ncbi.nlm.nih.gov/pubmed/18820725 http://dx.doi.org/10.1371/journal.pone.0003292

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