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Successful Inhibition of Tumor Development by Specific Class-3 Semaphorins Is Associated with Expression of Appropriate Semaphorin Receptors by Tumor Cells

The class-3 semaphorins (sema3s) include seven family members. Six of them bind to neuropilin-1 (np1) or neuropilin-2 (np2) receptors or to both, while the seventh, sema3E, binds to the plexin-D1 receptor. Sema3B and sema3F were previously characterized as tumor suppressors and as inhibitors of tumo...

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Detalles Bibliográficos
Autores principales: Kigel, Boaz, Varshavsky, Asya, Kessler, Ofra, Neufeld, Gera
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2538586/
https://www.ncbi.nlm.nih.gov/pubmed/18818766
http://dx.doi.org/10.1371/journal.pone.0003287