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Type I interferon-dependent gene MxA in perinatal HIV-infected patients under antiretroviral therapy as marker for therapy failure and blood plasmacytoid dendritic cells depletion

BACKGROUND: To determine the role of interferon-alpha in controlling HIV infection we phenotypically and functionally analyzed circulating plasmacytoid dendritic cells (pDC), which are known to be the highest interferon-alpha producing cells, in 33 perinatally infected HIV(+ )patients undergoing sta...

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Detalles Bibliográficos
Autores principales: Badolato, Raffaele, Ghidini, Claudia, Facchetti, Fabio, Serana, Federico, Sottini, Alessandra, Chiarini, Marco, Spinelli, Elena, Lonardi, Silvia, Plebani, Alessandro, Caimi, Luigi, Imberti, Luisa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542353/
https://www.ncbi.nlm.nih.gov/pubmed/18782441
http://dx.doi.org/10.1186/1479-5876-6-49