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Fregene: Simulation of realistic sequence-level data in populations and ascertained samples

BACKGROUND: FREGENE simulates sequence-level data over large genomic regions in large populations. Because, unlike coalescent simulators, it works forwards through time, it allows complex scenarios of selection, demography, and recombination to be modelled simultaneously. Detailed tracking of sites...

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Detalles Bibliográficos
Autores principales: Chadeau-Hyam, Marc, Hoggart, Clive J, O'Reilly, Paul F, Whittaker, John C, De Iorio, Maria, Balding, David J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542380/
https://www.ncbi.nlm.nih.gov/pubmed/18778480
http://dx.doi.org/10.1186/1471-2105-9-364