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Symplastic scrotal leiomyoma: a case report

INTRODUCTION: Scrotal leiomyomas are rare tumours which are essentially benign. Recurrence and malignant transformation to leiomyosarcoma have been reported. However, a specific subgroup with increased bizarre nuclei showing increased mitosis raises the need for a closer follow-up. We report on such...

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Detalles Bibliográficos
Autores principales: Philip, Joe, Manikandan, Ramaswamy, Vishwanathan, Palaniswamy, Mathew, Joseph
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542396/
https://www.ncbi.nlm.nih.gov/pubmed/18782437
http://dx.doi.org/10.1186/1752-1947-2-295
Descripción
Sumario:INTRODUCTION: Scrotal leiomyomas are rare tumours which are essentially benign. Recurrence and malignant transformation to leiomyosarcoma have been reported. However, a specific subgroup with increased bizarre nuclei showing increased mitosis raises the need for a closer follow-up. We report on such a case. CASE PRESENTATION: We report the case of a 65-year-old man who underwent a scrotal lump excision. Histology showed a well defined leiomyoma. The presence of nuclear pleomorphism and mitoses, just falling short of the criteria for malignancy, made prediction of biological behaviour difficult. The patient remains well on 4-year follow-up. CONCLUSION: Histological evidence of increased mitosis raises the need for sustained follow-up in view of the malignant potential from the extent of mitosis. Immunohistochemistry helps in identifying those patients warranting close follow-up.