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Symplastic scrotal leiomyoma: a case report

INTRODUCTION: Scrotal leiomyomas are rare tumours which are essentially benign. Recurrence and malignant transformation to leiomyosarcoma have been reported. However, a specific subgroup with increased bizarre nuclei showing increased mitosis raises the need for a closer follow-up. We report on such...

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Detalles Bibliográficos
Autores principales: Philip, Joe, Manikandan, Ramaswamy, Vishwanathan, Palaniswamy, Mathew, Joseph
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542396/
https://www.ncbi.nlm.nih.gov/pubmed/18782437
http://dx.doi.org/10.1186/1752-1947-2-295
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author Philip, Joe
Manikandan, Ramaswamy
Vishwanathan, Palaniswamy
Mathew, Joseph
author_facet Philip, Joe
Manikandan, Ramaswamy
Vishwanathan, Palaniswamy
Mathew, Joseph
author_sort Philip, Joe
collection PubMed
description INTRODUCTION: Scrotal leiomyomas are rare tumours which are essentially benign. Recurrence and malignant transformation to leiomyosarcoma have been reported. However, a specific subgroup with increased bizarre nuclei showing increased mitosis raises the need for a closer follow-up. We report on such a case. CASE PRESENTATION: We report the case of a 65-year-old man who underwent a scrotal lump excision. Histology showed a well defined leiomyoma. The presence of nuclear pleomorphism and mitoses, just falling short of the criteria for malignancy, made prediction of biological behaviour difficult. The patient remains well on 4-year follow-up. CONCLUSION: Histological evidence of increased mitosis raises the need for sustained follow-up in view of the malignant potential from the extent of mitosis. Immunohistochemistry helps in identifying those patients warranting close follow-up.
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spelling pubmed-25423962008-09-18 Symplastic scrotal leiomyoma: a case report Philip, Joe Manikandan, Ramaswamy Vishwanathan, Palaniswamy Mathew, Joseph J Med Case Reports Case Report INTRODUCTION: Scrotal leiomyomas are rare tumours which are essentially benign. Recurrence and malignant transformation to leiomyosarcoma have been reported. However, a specific subgroup with increased bizarre nuclei showing increased mitosis raises the need for a closer follow-up. We report on such a case. CASE PRESENTATION: We report the case of a 65-year-old man who underwent a scrotal lump excision. Histology showed a well defined leiomyoma. The presence of nuclear pleomorphism and mitoses, just falling short of the criteria for malignancy, made prediction of biological behaviour difficult. The patient remains well on 4-year follow-up. CONCLUSION: Histological evidence of increased mitosis raises the need for sustained follow-up in view of the malignant potential from the extent of mitosis. Immunohistochemistry helps in identifying those patients warranting close follow-up. BioMed Central 2008-09-09 /pmc/articles/PMC2542396/ /pubmed/18782437 http://dx.doi.org/10.1186/1752-1947-2-295 Text en Copyright © 2008 Philip et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Philip, Joe
Manikandan, Ramaswamy
Vishwanathan, Palaniswamy
Mathew, Joseph
Symplastic scrotal leiomyoma: a case report
title Symplastic scrotal leiomyoma: a case report
title_full Symplastic scrotal leiomyoma: a case report
title_fullStr Symplastic scrotal leiomyoma: a case report
title_full_unstemmed Symplastic scrotal leiomyoma: a case report
title_short Symplastic scrotal leiomyoma: a case report
title_sort symplastic scrotal leiomyoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542396/
https://www.ncbi.nlm.nih.gov/pubmed/18782437
http://dx.doi.org/10.1186/1752-1947-2-295
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AT mathewjoseph symplasticscrotalleiomyomaacasereport