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Symplastic scrotal leiomyoma: a case report
INTRODUCTION: Scrotal leiomyomas are rare tumours which are essentially benign. Recurrence and malignant transformation to leiomyosarcoma have been reported. However, a specific subgroup with increased bizarre nuclei showing increased mitosis raises the need for a closer follow-up. We report on such...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542396/ https://www.ncbi.nlm.nih.gov/pubmed/18782437 http://dx.doi.org/10.1186/1752-1947-2-295 |
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author | Philip, Joe Manikandan, Ramaswamy Vishwanathan, Palaniswamy Mathew, Joseph |
author_facet | Philip, Joe Manikandan, Ramaswamy Vishwanathan, Palaniswamy Mathew, Joseph |
author_sort | Philip, Joe |
collection | PubMed |
description | INTRODUCTION: Scrotal leiomyomas are rare tumours which are essentially benign. Recurrence and malignant transformation to leiomyosarcoma have been reported. However, a specific subgroup with increased bizarre nuclei showing increased mitosis raises the need for a closer follow-up. We report on such a case. CASE PRESENTATION: We report the case of a 65-year-old man who underwent a scrotal lump excision. Histology showed a well defined leiomyoma. The presence of nuclear pleomorphism and mitoses, just falling short of the criteria for malignancy, made prediction of biological behaviour difficult. The patient remains well on 4-year follow-up. CONCLUSION: Histological evidence of increased mitosis raises the need for sustained follow-up in view of the malignant potential from the extent of mitosis. Immunohistochemistry helps in identifying those patients warranting close follow-up. |
format | Text |
id | pubmed-2542396 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-25423962008-09-18 Symplastic scrotal leiomyoma: a case report Philip, Joe Manikandan, Ramaswamy Vishwanathan, Palaniswamy Mathew, Joseph J Med Case Reports Case Report INTRODUCTION: Scrotal leiomyomas are rare tumours which are essentially benign. Recurrence and malignant transformation to leiomyosarcoma have been reported. However, a specific subgroup with increased bizarre nuclei showing increased mitosis raises the need for a closer follow-up. We report on such a case. CASE PRESENTATION: We report the case of a 65-year-old man who underwent a scrotal lump excision. Histology showed a well defined leiomyoma. The presence of nuclear pleomorphism and mitoses, just falling short of the criteria for malignancy, made prediction of biological behaviour difficult. The patient remains well on 4-year follow-up. CONCLUSION: Histological evidence of increased mitosis raises the need for sustained follow-up in view of the malignant potential from the extent of mitosis. Immunohistochemistry helps in identifying those patients warranting close follow-up. BioMed Central 2008-09-09 /pmc/articles/PMC2542396/ /pubmed/18782437 http://dx.doi.org/10.1186/1752-1947-2-295 Text en Copyright © 2008 Philip et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Philip, Joe Manikandan, Ramaswamy Vishwanathan, Palaniswamy Mathew, Joseph Symplastic scrotal leiomyoma: a case report |
title | Symplastic scrotal leiomyoma: a case report |
title_full | Symplastic scrotal leiomyoma: a case report |
title_fullStr | Symplastic scrotal leiomyoma: a case report |
title_full_unstemmed | Symplastic scrotal leiomyoma: a case report |
title_short | Symplastic scrotal leiomyoma: a case report |
title_sort | symplastic scrotal leiomyoma: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542396/ https://www.ncbi.nlm.nih.gov/pubmed/18782437 http://dx.doi.org/10.1186/1752-1947-2-295 |
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