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Orientation and structure of the Ndc80 complex on the microtubule lattice

The four-subunit Ndc80 complex, comprised of Ndc80/Nuf2 and Spc24/Spc25 dimers, directly connects kinetochores to spindle microtubules. The complex is anchored to the kinetochore at the Spc24/25 end, and the Ndc80/Nuf2 dimer projects outward to bind to microtubules. Here, we use cryoelectron microsc...

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Detalles Bibliográficos
Autores principales:	Wilson-Kubalek, Elizabeth M., Cheeseman, Iain M., Yoshioka, Craig, Desai, Arshad, Milligan, Ronald A.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542468/ https://www.ncbi.nlm.nih.gov/pubmed/18794333 http://dx.doi.org/10.1083/jcb.200804170

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