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Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells
Lis1 and Ndel1 are essential for animal development. They interact directly with one another and with cytoplasmic dynein. The developing brain is especially sensitive to reduced Lis1 or Ndel1 levels, as both proteins influence spindle orientation, neural cell fate decisions, and neuronal migration....
Autores principales: | Hebbar, Sachin, Mesngon, Mariano T., Guillotte, Aimee M., Desai, Bhavim, Ayala, Ramses, Smith, Deanna S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542469/ https://www.ncbi.nlm.nih.gov/pubmed/18809722 http://dx.doi.org/10.1083/jcb.200803071 |
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