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Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster
Notch-mediated cell–cell communication regulates numerous developmental processes and cell fate decisions. Through a mosaic genetic screen in Drosophila melanogaster, we identified a role in Notch signaling for a conserved thiol oxidase, endoplasmic reticulum (ER) oxidoreductin 1–like (Ero1L). Altho...
Autores principales: | Tien, An-Chi, Rajan, Akhila, Schulze, Karen L., Ryoo, Hyung Don, Acar, Melih, Steller, Hermann, Bellen, Hugo J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542473/ https://www.ncbi.nlm.nih.gov/pubmed/18809725 http://dx.doi.org/10.1083/jcb.200805001 |
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