Cargando…

Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction

A prominent feature of synaptic maturation at the neuromuscular junction (NMJ) is the topological transformation of the acetylcholine receptor (AChR)-rich postsynaptic membrane from an ovoid plaque into a complex array of branches. We show here that laminins play an autocrine role in promoting this...

Descripción completa

Detalles Bibliográficos
Autores principales: Nishimune, Hiroshi, Valdez, Gregorio, Jarad, George, Moulson, Casey L., Müller, Ulrich, Miner, Jeffrey H., Sanes, Joshua R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542479/
https://www.ncbi.nlm.nih.gov/pubmed/18794334
http://dx.doi.org/10.1083/jcb.200805095

Ejemplares similares