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Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction
A prominent feature of synaptic maturation at the neuromuscular junction (NMJ) is the topological transformation of the acetylcholine receptor (AChR)-rich postsynaptic membrane from an ovoid plaque into a complex array of branches. We show here that laminins play an autocrine role in promoting this...
Autores principales: | Nishimune, Hiroshi, Valdez, Gregorio, Jarad, George, Moulson, Casey L., Müller, Ulrich, Miner, Jeffrey H., Sanes, Joshua R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542479/ https://www.ncbi.nlm.nih.gov/pubmed/18794334 http://dx.doi.org/10.1083/jcb.200805095 |
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