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EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial–mesenchymal transition

EPB41L5 belongs to the band 4.1 superfamily. We investigate here the involvement of EPB41L5 in epithelial–mesenchymal transition (EMT) during mouse gastrulation. EPB41L5 expression is induced during TGFβ-stimulated EMT, whereas silencing of EPB41L5 by siRNA inhibits this transition. In EPB41L5 mutan...

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Detalles Bibliográficos
Autores principales:	Hirano, Mariko, Hashimoto, Shigeru, Yonemura, Shigenobu, Sabe, Hisataka, Aizawa, Shinichi
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2542480/ https://www.ncbi.nlm.nih.gov/pubmed/18794329 http://dx.doi.org/10.1083/jcb.200712086

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